Gabriëlle Tuijthof was born in Tehran, Iran, in 1975. She graduated cum laude in Mechanical Engineering at Delft University of Technology in 1998, specializing in human-machine systems. Her PhD thesis, which was completed both at Delft University of Technology in Delft and at the Amsterdam University Medical Center (location AMC) in Amsterdam, researched the development of new surgical techniques for exploratory surgery in joints. "I am passionate about the human body; especially the musculoskeletal structures have my interest. It is fascinating to discover how well humans are adapted to perform complex precise actions. With this interest and the drive to contribute meaningfully to society.

Dr. Jan-Arne Gewert as Entrepreneur of the Year and successful Managing Director of mid-size enterprises, Dr. Jan-Arne Gewert has many years of practical experience in business. Since 2015 he consults managers in economy and research in questions of business as well as strategy development. He is a member of the Federal Association of German Management Consultants and Ambassador of the Global-Ethic Institute. As a lecturer in general management, he passes on his knowledge to students at universities of applied sciences in Germany and Switzerland.

Jan Michael Olaf is Professor and Director of the Study Center of IT Management and Computer Science at Baden-Wuerttemberg Cooperative State University (DHBW) in Lörrach (Germany) since 2015. He has graduated in Physics at Freiburg University with a Ph.D. from the faculty of Physics in cooperation with Fraunhofer Institute for Mechanics of Materials in Freiburg. After 20 years of experience in automation and IT industry and various executive positions in business IT and education he continued his academic carreer in the research area of industrial internet of things (IIoT), augmented and mixed reality applications, (digital) business transformation and innovative business models at DHBW Lörrach.

Julia Rausenberger is Professor in Applied Mathematics in Life Sciences at the University of Applied Sciences Northwestern Switzerland. After studying mathematics at the universities of Münster and Tübingen (D), she carried out research in various interdisciplinary research projects with biotechnologists and biologists and received her PhD in the field of systems biology from the University of Freiburg (D). Throughout her years of teaching experience, she has focused on combining mathematical knowledge transfer with life science applications using student-oriented didactic preparation. Having an agile mindset, she uses eduScrum as a teaching framework and promotes students' personal and academic development, for example through qualification of tutors. She sets didactic priorities in her teaching, thus developing future-oriented teaching and learning scenarios as well as organizational structures. In addition to mathematical expertise, Julia's students - the scientists and engineers of tomorrow - acquire vital 21st century skills such as collaboration and communication.

Witold Habrat is an Associate Professor of the Rzeszów University of Technology. In 2006 he obtained PhD degree and in 2019 he gained his habilitation in mechanical engineering. Professor Witold Habrat has participated in several research projects in the field of machining of difficult-to-cut materials, mostly in cooperation with the aerospace industry. Keynote will be focused on "Sustainable machining of titanium and its alloys" The wide and various application of titanium and its alloys is related to the necessity of manufacturing machine parts while maintaining adequate construction requirements. Nowadays, it is important that the manufacturing process should also incorporate the aspects of the sustainable machining taking into consideration questions of economy, environment and social implications related to production. Those requirements determine the technological approach to the process of machining.

Jaroslava Svobodová is an assistant professor in the field Technology and materials on Faculty of Mechanical Engineering - University of J. E. Purkyně in Ústí nad Labem, Czech Republic. Currently, she works at the Department of Technology and Materials, she is redactor of the Manufacturing Technology journal and the manager and the researcher in the Operational Programme Research, Development and Education (OP RDE) - Development of new nano-coatings and micro- coatings on the surface of selected metallic materials. Areas of her activity are material science, materials failures due to the corrosion, fractures and limit states, manufacturing technology, etc.

In today's competitive business world, companies need to present new perspectives to market and sell the goods they manufacture. In this context, as a new approach, the value-based manufacturing can be defined as the manufacturing that providers are paid based on the amount of the services they deliver rather than fee-for-service or capitated approach in classical manufacturing approaches. This new approach. This new approach will lead to radical changes in manufacturing systems with its integration to industry 4.0.

The sustainability issues are trendy due to the environmental problems caused by an unbridled use of the resources. Governments are making efforts aiming to increase the industrial sensibility to environmental problems promoting actions to reduce the impact of their activities. Processes and manufacturing technologies are involved in finding solutions having a lower environmental impact. A method to evaluate the sustainability of the micro-Electrical Discharge Machining (EDM), using quantitative and qualitative indicators, is developed taking into account the critical aspects of the technology. This method can support in the finding of the process conditions that minimize the environmental impact. The critical aspects are highlighted making possible the promotion of actions that improve the sustainability of the process. I´m happy to introduce professor Chiara Ravassio. She was born in Bergamo (Italy) in 1974. Degree in Industrial Engineering at University of Bergamo in 1999. Ph.D in "Manufacturing and Production Systems" by Politecnico of Milano. In 2003 "Marie Curie" grant for six months by Institut fuer Werkstoffkunde of Hannover. Professor assistant of Manufacturing and Production Systems at the Mechanical Engineering Faculty of the University of Bergamo from 2005. Professor of several courses (Innovative Manufacturing Technologies, Manufacturing Studies and Mechanical Technology) of the master degree in Mechanical Engineering at the Faculty of Engineering at the University of Bergamo. Her research area are the unconventional technologies, micromachining and sustainability aspects of the technologies.

Professor Alessandro Ruggiero. He was born in Salerno, he graduated "cum laude" in Mechanical Engineering at the University of Salerno. In 1997 he attended the Tribology PhD course (University of Pisa). From 1999 to 2005 he has been Assistant Professor at University of Salerno and from 2005 till now is Associate Professor. In 2017 he gained the National habilitation to Full Professor. He is author of more than 170 scientific papers on (Bio) Tribology and lubrication, noise and vibration control and biomechanics